Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209480 | 0.85 | PDE4D (0.59) | SMN1; SMN2MAPK10HTTMAPTKDM4E | |
| SCHEMBL28346436 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK10HTTMAPTKDM4E | |
| SCHEMBL3262663 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3265324 | 0.78 | PDE4D (0.53) | SMN1; SMN2MAPK10HTTMAPTKDM4E | |
| SCHEMBL17279852 | 0.77 | HPGDS (0.60) | SMN1; SMN2MAPK10HTTMAPTKDM4E | |
| SCHEMBL3260996 | 0.76 | PDE4D (0.69) | SMN1; SMN2MAPK10HTTMAPTKDM4E | |
| SCHEMBL6852749 | 0.76 | KDM4E (0.57) | SMN1; SMN2MAPK10HTTMAPTKDM4E | |
| SCHEMBL3263722 | 0.76 | HPGDS (0.57) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3260077 | 0.75 | TTK (0.42) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3261776 | 0.75 | MAPK1 (0.50) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |