Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390203 | 0.91 | MAPK1 (0.43) | MAPK1NPSR1RPS6KA3TTKCNR1 | |
| SCHEMBL3260077 | 0.83 | TTK (0.42) | MAPK1NPSR1TTKCNR1CNR2 | |
| SCHEMBL3260006 | 0.83 | CHEK1 (0.56) | MAPK1NPSR1TTKCNR1CNR2 | |
| SCHEMBL12398406 | 0.82 | NFKB1 (0.46) | MAPK1NPSR1TTKCNR1CNR2 | |
| SCHEMBL13495080 | 0.78 | L3MBTL1 (0.55) | TTKCNR1CNR2GPR55AKT2 | |
| SCHEMBL13495378 | 0.75 | SMN1; SMN2 (0.52) | NPSR1MAPTGAAKDM4ENPC1 | |
| SCHEMBL5865715 | 0.71 | AKT2 (0.68) | MAPK1NPSR1RPS6KA3GRM5AKT2 | |
| SCHEMBL13495274 | 0.70 | HPGD (0.35) | MAPK1CNR1CNR2GPR55MAPT | |
| SCHEMBL3263121 | 0.69 | MAPK1 (0.43) | MAPK1TTKCNR1CNR2GPR55 | |
| SCHEMBL5231898 | 0.69 | KDM4E (0.62) | MAPK1NPSR1RPS6KA3TTKCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |