Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261776 | 0.83 | MAPK1 (0.50) | TTKMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3390203 | 0.76 | MAPK1 (0.43) | TTKMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL13495378 | 0.75 | SMN1; SMN2 (0.52) | MAPTGAAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3260006 | 0.73 | CHEK1 (0.56) | TTKMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL12398406 | 0.72 | NFKB1 (0.46) | TTKMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL17156157 | 0.71 | LRRK2 (0.46) | SMN1; SMN2HSD17B10MAPK1CNR1CNR2 | |
| SCHEMBL2375096 | 0.71 | AKT2 (0.52) | GAAALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3263121 | 0.69 | MAPK1 (0.43) | TTKMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13495080 | 0.69 | L3MBTL1 (0.55) | TTKMAPTSQORCNR1CNR2 | |
| SCHEMBL8430557 | 0.67 | CNR1 (0.59) | TTKGAAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |