Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPD | P32754 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495634 | 0.84 | POLB (0.44) | GAAKMT2APIK3CDPIK3CAMTOR | |
| SCHEMBL13495635 | 0.81 | ALDH1A1 (0.43) | KMT2ATP53KDM4EPOLBGSR | |
| SCHEMBL13495669 | 0.80 | PTGS2 (0.51) | POLBGSRALDH3A1PTGS1PTGS2 | |
| SCHEMBL13495638 | 0.79 | PTGS2 (0.47) | GAAKMT2APOLBGSRALDH3A1 | |
| SCHEMBL13495691 | 0.77 | SCN9A (0.49) | KMT2AKDM4EPTGS2PKMMEN1 | |
| SCHEMBL13495644 | 0.77 | HTT (0.48) | PIK3CDPIK3CAMTORHPDPOLB | |
| SCHEMBL13495586 | 0.75 | PIK3CA (0.60) | TP53PIK3CDPIK3CAMTORHPD | |
| SCHEMBL13495671 | 0.74 | POLB (0.42) | GAAPIK3CDPIK3CAMTORHPD | |
| SCHEMBL13495641 | 0.74 | HPD (0.47) | KMT2ATP53PIK3CDPIK3CAMTOR | |
| SCHEMBL13329865 | 0.74 | CA1 (0.59) | GAATP53POLBPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012745-A2 | BENZIMIDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |