Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12237083 | 1.00 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAHPGDALOX15 | |
| SCHEMBL13267564 | 0.83 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL13078359 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LMNACYP2C9 | |
| SCHEMBL464624 | 0.82 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNAHPGDALOX15 | |
| SCHEMBL10109154 | 0.82 | THRB (0.41) | ALDH1A1SMN1; SMN2LMNAHPGDALOX15 | |
| SCHEMBL10020569 | 0.78 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAHPGDALOX15 | |
| SCHEMBL24328680 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAHPGDALOX15 | |
| SCHEMBL12183703 | 0.77 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL12138460 | 0.75 | — | — | |
| SCHEMBL19368104 | 0.73 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019004012-A1 | COMPOSITION FOR DYEING KERATIN FIBERS | L'OREAL (FR) | 2019-01-03 | — | — | WO | claimed |
| WO-2019004012-A1 | COMPOSITION FOR DYEING KERATIN FIBERS | L'OREAL (FR) | 2019-01-03 | — | — | WO | disclosed |
| US-20170290827-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD PHARMASSET LLC | 2017-10-12 | — | — | US | disclosed |
| EP-2368888-B1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | SUMITOMO SEIKA CHEMICALS (JP) | 2014-03-26 | — | — | EP | disclosed |
| EP-2705893-A1 | Process for separating acid-containing gas mixtures | Solvay SA (BE) | 2014-03-12 | — | — | EP | disclosed |
| US-20140012018-A1 | SULFOLANE COMPOSITION | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2014-01-09 | — | — | US | disclosed |
| US-8436193-B2 | Method for manufacturing sulfolene compound and method for manufacturing sulfolane compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20110288307-A1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| EP-2368888-A1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | Sumitomo Seika Chemicals CO. LTD. (JP) | 2011-09-28 | — | — | EP | disclosed |
| US-5102777-A | Immersion solution consists of a solvent, amine and fatty acid , corrosion and chemical resistance to underlying metal layer | ARDROX INC. (US) | 1992-04-07 | — | — | US | disclosed |
| US-3932317-A | AMMONIA, SURFACTANTS, SULFOLANES | PHILLIPS PETROLEUM COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290827-A1 | INHIBITORS OF HEPATITIS C VIRUS | HAVCR2, SLC10A1, GOT1 | ALDH1A1 112/4885SMN1; SMN2 4128/4885LMNA 2502/4885 |
| US-20110288307-A1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | SULT1A1, STS, SULT2A1 | ALDH1A1 43/4885SMN1; SMN2 445/4885LMNA 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.