Methoxymethane

Methoxymethane

SCHEMBL135046

COC.O=C(O)CCc1ccccc1C(=O)C(O)c1ccccc1

nearest known ligand 0.46

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
ALDH1A1 P00352 2/20 0.46
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
FFAR1 O14842 1/20 0.42
MAPK1 P28482 1/20 0.40
KDM4E B2RXH2 1/20 0.39
KEAP1 Q14145 1/20 0.39
POLB P06746 1/20 0.38
PTGER1 P34995 1/20 0.38
PTGER4 P35408 1/20 0.38
PTGER3 P43115 1/20 0.38
PTGER2 P43116 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL7628233 0.84 LMNA (0.47) LMNAALDH1A1CES2CES1MAPK1
SCHEMBL4929020 0.82 NAAA (0.48) LMNAALDH1A1CES2CES1MAPK1
Methoxymethane SCHEMBL8661498 0.82 LMNA (0.41) LMNAALDH1A1CES2CES1MAPK1
SCHEMBL452704 0.82 LMNA (0.49) LMNAALDH1A1CES2CES1MAPK1
Methoxymethane SCHEMBL2190404 0.81 ALDH1A1 (0.46) LMNAALDH1A1CES2CES1MAPK1
SCHEMBL30070901 0.80 LMNA (0.50) LMNAALDH1A1CES2CES1MAPK1
Benzoin SCHEMBL28288426 0.80 LMNA (0.60) LMNAALDH1A1CES2CES1MAPK1
Benzene SCHEMBL28132336 0.80 LMNA (0.53) LMNAALDH1A1CES2CES1MAPK1
SCHEMBL13601942 0.80 KEAP1 (0.47) LMNAALDH1A1FFAR1MAPK1KDM4E
SCHEMBL390944 0.80 LMNA (0.53) LMNAALDH1A1CES2CES1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9279038-B2 Method for producing cross-linked elastomer SEMPERIT AKTIENGESELLSCHAFT HOLDING (AT) 2016-03-08 US disclosed
EP-1762586-B1 Method for producing a crosslinked elastomer SEMPERIT AG HOLDING (AT) 2012-03-07 EP disclosed
US-20070105971-A1 METHOD FOR PRODUCING CROSS-LINKED ELASTOMER SEMPERIT AKTIENGESELLSCHAFT HOLDING (AT) 2007-05-10 US disclosed
EP-1762586-A2 Method for producing a crosslinked elastomer Semperit Aktiengesellschaft Holding (AT) 2007-03-14 EP disclosed