Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508420 | 0.90 | CYP1A2 (0.42) | ESR1CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14570727 | 0.89 | CYP1A2 (0.41) | ESR1CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13508382 | 0.89 | ESR1 (0.45) | ESR1CYP2D6PLAUPTGS2CYP19A1 | |
| SCHEMBL13508451 | 0.84 | PTGS1 (0.43) | ESR1PLAUCYP3A4PTGS2MEN1 | |
| SCHEMBL14077314 | 0.83 | RELA (0.36) | ESR1CYP2D6PLAUCYP1A2CYP3A4 | |
| SCHEMBL13380719 | 0.82 | ESR1 (0.44) | ESR1CYP2D6PLAUPTGS2CYP19A1 | |
| SCHEMBL13508400 | 0.82 | CYP1A2 (0.42) | CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5877773 | 0.79 | NR4A1 (0.48) | ESR1CYP2D6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16231505 | 0.79 | ESR1 (0.36) | ESR1CYP2D6PTGS2CYP19A1CYP11B2 | |
| SCHEMBL13511074 | 0.77 | CYP19A1 (0.36) | ESR1CYP2D6PTGS2CYP19A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761962-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2010-02-03 | — | — | EP | disclosed |
| US-20090159874-A1 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090159874-A1 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090159874-A1 | Organic electroluminescent devices | LEF1, NCS1, CRY1 | ESR1 356/4885CYP2D6 1428/4885PLAU 3072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.