Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508382 | 0.95 | ESR1 (0.45) | PTGS1PTGS2ESR1ESR2KDM4E | |
| SCHEMBL13380719 | 0.88 | ESR1 (0.44) | PTGS2ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL13508399 | 0.84 | ESR1 (0.36) | PTGS2ESR1MEN1CYP3A4KMT2A | |
| SCHEMBL2964613 | 0.84 | CES2 (0.47) | PTGS1PTGS2ESR1ESR2CES2 | |
| SCHEMBL13380720 | 0.83 | ESR1 (0.37) | PTGS1PTGS2ESR1ESR2KDM4E | |
| SCHEMBL13380721 | 0.82 | KMO (0.36) | PTGS2ESR1ALDH1A1MAPTMAPK1 | |
| SCHEMBL14003792 | 0.82 | PTGS2 (0.44) | PTGS2ESR1ALDH1A1MAPTHPGD | |
| SCHEMBL11988518 | 0.82 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL11988086 | 0.82 | AKR1C3 (0.38) | PTGS2ESR1ESR2CES2CES1 | |
| SCHEMBL13992021 | 0.80 | ESR1 (0.57) | PTGS2ESR1ESR2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761962-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2010-02-03 | — | — | EP | disclosed |
| US-20090159874-A1 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090159874-A1 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090159874-A1 | Organic electroluminescent devices | LEF1, NCS1, CRY1 | PTGS1 2375/4885PTGS2 3216/4885ESR1 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.