Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12870190 | 0.85 | STAT3 (0.46) | ALDH1A1GAARAB9AKMT2AMEN1 | |
| SCHEMBL11545447 | 0.78 | ALDH1A1 (0.53) | ALDH1A1GAAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL12045345 | 0.77 | L3MBTL1 (0.48) | ALDH1A1GAAKMT2AMEN1CA12 | |
| SCHEMBL570839 | 0.77 | ALDH1A1 (0.73) | ALDH1A1GAAKDM4ENPC1HPGD | |
| SCHEMBL13956708 | 0.77 | ALDH1A1 (0.44) | ALDH1A1GAAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL8866856 | 0.77 | STAT3 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1STAT3 | |
| SCHEMBL17222796 | 0.76 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2AMEN1STAT3 | |
| SCHEMBL12522073 | 0.76 | ALDH1A1 (0.43) | ALDH1A1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14018774 | 0.75 | ALDH1A1 (0.45) | ALDH1A1GAAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL28486120 | 0.75 | ALDH1A1 (0.50) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090022772-A1 | BIOABSORBABLE ELASTOMERIC ARTERIAL SUPPORT DEVICE AND METHODS OF USE | MEDIVAS, LLC (US) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090022772-A1 | BIOABSORBABLE ELASTOMERIC ARTERIAL SUPPORT DEVICE AND METHODS OF USE | BCAT1, VEGFA, ADM2 | ALDH1A1 1846/4885GAA 1775/4885KDM4E 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.