SCHEMBL1352503

SCHEMBL1352503

Nc1cccc(Oc2ccccc2N)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.68
GAA P10253 3/20 0.68
MAOB P27338 2/20 0.64
RCE1 Q9Y256 1/20 0.61
MAPT P10636 3/20 0.52
POLB P06746 1/20 0.52
HSP90AA1 P07900 1/20 0.52
CYP3A4 P08684 3/20 0.50
TLR4 O00206 1/20 0.49
KDM4E B2RXH2 1/20 0.47
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
TP53 P04637 1/20 0.46
MEN1 O00255 1/20 0.45
MITF O75030 1/20 0.45
GFER P55789 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28499448 0.96 MAOB (0.66) ALDH1A1GAAMAOBRCE1MAPT
SCHEMBL707810 0.90 MAOB (0.72) ALDH1A1GAAMAOBRCE1MAPT
SCHEMBL29929290 0.90 MAOB (0.72) ALDH1A1GAAMAOBRCE1MAPT
SCHEMBL1049509 0.90 ALDH1A1 (0.75) ALDH1A1GAAMAOBRCE1MAPT
SCHEMBL6289782 0.88 ALDH1A1 (0.72) ALDH1A1GAAMAOBRCE1MAPT
SCHEMBL1270958 0.88 ALDH1A1 (0.72) ALDH1A1GAAMAOBRCE1MAPT
Ammonia Solution, Strong SCHEMBL10884991 0.88 ALDH1A1 (0.72) ALDH1A1GAAMAOBRCE1MAPT
SCHEMBL6290404 0.88 ALDH1A1 (0.72) ALDH1A1GAAMAOBRCE1MAPT
SCHEMBL1270999 0.88 ALDH1A1 (0.72) ALDH1A1GAAMAOBRCE1MAPT
SCHEMBL1271585 0.88 MAOB (0.69) ALDH1A1GAAMAOBRCE1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146113-A Sizing agent and preparation method and application thereof 东华大学 2024-06-07 CN claimed
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INST SCI & TECH (KR) 2018-03-08 US claimed
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-07-07 US claimed
EP-2940015-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT Korea Advanced Institute of Science and Technology (KR) 2015-11-04 EP claimed
US-20150045481-A1 Asymmetric Diamine Compounds Containing Two Functional Groups and Polymers Therefrom KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-02-12 US claimed
US-5077377-A Process for preparing melt-processible aromatic polyamides with alkali metal fluoride catalyst E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-31 US claimed
JP-6263698-A None JP disclosed
CN-107533259-B Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学工业株式会社 2024-06-21 CN disclosed
CN-118146113-A Sizing agent and preparation method and application thereof 东华大学 2024-06-07 CN disclosed
CN-118043732-A Weak anchoring liquid crystal aligning agent, liquid crystal display element and polymer 日产化学株式会社 2024-05-14 CN disclosed
WO-2024058164-A1 LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2024-03-21 WO disclosed
CN-117460990-A Weak anchoring liquid crystal aligning agent, liquid crystal display element and copolymer 日产化学株式会社 2024-01-26 CN disclosed
CN-117120516-A Polyimide, resin composition, polyimide film, and method for producing same 旭化成株式会社 2023-11-24 CN disclosed
US-5286840-A Reacting in presence of a dicarboxylic acid anhydride MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-15 US disclosed
US-5283313-A Blocked with dicarboxylic acid anhydride MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-01 US disclosed
US-5268446-A Melt processable; end blocked with phthalic anhydride MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-12-07 US disclosed
US-5268447-A End blocked with phthalic anhydride MITSUI TOATSU CHEMICALS, INC. (JP) 1993-12-07 US disclosed
EP-0488630-A2 Thermally stable polyimide and preparation process of polyimide MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-06-03 EP disclosed
EP-0488604-A2 Readily processable polyimide, preparation process of polyimide, and resin composition of polyimide MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-06-03 EP disclosed
EP-0459801-A2 Readily processable polyimide and preparation process of same MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-12-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150045481-A1 Asymmetric Diamine Compounds Containing Two Functional Groups and Polymers Therefrom AOC1, INMT, PRMT6 ALDH1A1 1726/4885GAA 4337/4885MAOB 565/4885
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT RICTOR, SGTA, SLC43A1 ALDH1A1 1659/4885GAA 2373/4885MAOB 4063/4885
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT SGTA, RICTOR, SLC43A1 ALDH1A1 1627/4885GAA 2578/4885MAOB 4147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.