Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 5/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CACNB4 | O00305 | 3/20 | 0.41 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.41 |
| ▸ | CACNG3 | O60359 | 3/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.41 |
| ▸ | CACNB3 | P54284 | 3/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.41 |
| ▸ | CACNG7 | P62955 | 3/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.41 |
| ▸ | CACNG1 | Q06432 | 3/20 | 0.41 |
| ▸ | CACNB2 | Q08289 | 3/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354038 | 0.84 | NR1H2 (0.46) | NR1H2HTR6LMNAICMT | |
| SCHEMBL3351825 | 0.83 | ACHE (0.44) | NR1H2ACHECACNB4CACNA1ACACNA1G | |
| SCHEMBL13537232 | 0.82 | BCL6 (0.43) | HTR6CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL3352252 | 0.82 | CACNB4 (0.43) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL3358868 | 0.82 | NR1H2 (0.53) | NR1H2HTR6LMNAALDH1A1 | |
| SCHEMBL3352715 | 0.81 | HTR7 (0.59) | HTR6LMNACACNB4CACNA1ACACNA1G | |
| SCHEMBL3353653 | 0.79 | ACHE (0.50) | NR1H2ACHELMNACACNB4CACNA1A | |
| SCHEMBL3358037 | 0.77 | ALDH1A1 (0.40) | ACHEALDH1A1POLBTDP1HTR7 | |
| SCHEMBL3353615 | 0.76 | HRH3 (0.41) | ICMTKDM4E | |
| SCHEMBL3357851 | 0.75 | ICMT (0.54) | HTR6ACHECACNB4CACNA1ACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |