SCHEMBL1354136

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1351311	0.87	FADS1 (0.57)	HDAC8BCAT2HDAC1HDAC6PLAU
	SCHEMBL1354392	0.85	HDAC8 (0.58)	HDAC8BCAT2POLBALDH1A1LMNA
	SCHEMBL29929613	0.82	JAK2 (0.78)	HDAC8POLBALDH1A1LMNAJAK2
	SCHEMBL1353976	0.82	HDAC8 (0.77)	HDAC8POLBALDH1A1LMNAKMT2A
	SCHEMBL12134071	0.82	HDAC8 (0.51)	HDAC8BCAT2ALDH1A1LMNAHDAC1
	SCHEMBL18145960	0.81	HDAC8 (0.64)	HDAC8POLBALDH1A1LMNAPPARG
	SCHEMBL1353348	0.81	ALDH1A1 (0.52)	HDAC8BCAT2POLBALDH1A1LMNA
	SCHEMBL7329845	0.80	HDAC8 (0.67)	HDAC8POLBALDH1A1LMNAPPARG
	SCHEMBL20601659	0.80	HDAC8 (0.67)	HDAC8POLBALDH1A1LMNAPPARG
	SCHEMBL13408113	0.79	HDAC8 (0.58)	HDAC8ALDH1A1HDAC1HDAC6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.