SCHEMBL13543374

SCHEMBL13543374

CCNC(=O)N(O)c1cc(C)ccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 5/20 0.42
▸ LMNA P02545 3/20 0.41
▸ GAA P10253 2/20 0.41
▸ NPC1 O15118 2/20 0.41
▸ MAPT P10636 1/20 0.41
▸ HPGD P15428 2/20 0.38
▸ HCRTR1 O43613 1/20 0.37
▸ HCRTR2 O43614 1/20 0.37
▸ TSHR P16473 2/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ HSP90AA1 P07900 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ TAS1R3 Q7RTX0 1/20 0.35
▸ TAS1R1 Q7RTX1 1/20 0.35
▸ TAS1R2 Q8TE23 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ P2RX7 Q99572 4/20 0.34
▸ HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13543371 0.88 RAB9A (0.47) RAB9ANPC1HPGDHCRTR1HCRTR2
SCHEMBL879552 0.86 SMN1; SMN2 (0.43) LMNAGAAHPGDTSHRSMN1; SMN2
SCHEMBL879518 0.80 MAPT (0.50) LMNAMAPTHPGDHCRTR1HCRTR2
SCHEMBL2736489 0.80 ALDH1A1 (0.43) RAB9ALMNAGAANPC1HPGD
SCHEMBL13543373 0.79 ACACB (0.36) RAB9ALMNAGAANPC1MAPT
SCHEMBL19483171 0.77 FSCN1 (0.40) RAB9ALMNAGAANPC1MAPT
SCHEMBL10067205 0.76 TSHR (0.49) LMNAGAAMAPTHPGDTSHR
SCHEMBL11814814 0.75 RAB9A (0.44) RAB9ALMNANPC1MAPTHPGD
SCHEMBL12163930 0.74 LMNA (0.53) RAB9ALMNAGAANPC1MAPT
SCHEMBL14963059 0.72 LMNA (0.40) LMNAGAAHPGDTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9677053-B2 Laccases for bio-bleaching BASF ENZYMES LLC (US) 2017-06-13 — — US disclosed
US-20160237411-A1 LACCASES FOR BIO-BLEACHING VERENIUM CORPORATION 2016-08-18 — — US disclosed
US-9353477-B2 Laccases for bio-bleaching BASF ENZYMES LLC (US) 2016-05-31 — — US disclosed
US-20150125936-A1 LACCASES FOR BIO-BLEACHING BASF SE (DE) 2015-05-07 — — US disclosed
US-8951766-B2 Laccases for bio-bleaching BASF ENZYMES LLC (US) 2015-02-10 — — US disclosed
US-20130126110-A1 LACCASES FOR BIO-BLEACHING BASF SE (DE) 2013-05-23 — — US disclosed
US-8377670-B2 Laccases for bio-bleaching VERENIUM CORPORATION (US) 2013-02-19 — — US disclosed
US-20100018658-A1 Laccases for Bio-Bleaching VERENIUM CORPORATION (US) 2010-01-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100018658-A1 Laccases for Bio-Bleaching AOX1, GUSB, LPO RAB9A 2542/4885LMNA 693/4885GAA 79/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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