Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865107 | 0.71 | CASR (0.34) | HSD11B1 | |
| SCHEMBL15959034 | 0.65 | CASR (0.41) | HSD11B1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL13638260 | 0.65 | ALDH1A1 (0.35) | — | |
| SCHEMBL120298 | 0.64 | HSD11B1 (1.00) | HSD11B1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL120297 | 0.64 | HSD11B1 (1.00) | HSD11B1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL15675005 | 0.63 | HSD11B1 (0.45) | HSD11B1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL15959037 | 0.62 | HTR1A (0.44) | CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL13953687 | 0.62 | CASR (0.38) | — | |
| SCHEMBL957448 | 0.62 | CASR (0.38) | — | |
| SCHEMBL15368397 | 0.62 | GPR139 (0.35) | CYP2C9CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011314-A1 | CYCLIC INHIBITORS OF 11 BETA-HYDROXYSTEROID DEHYDROGENASE 1 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-28 | — | — | WO | disclosed |