SCHEMBL135567

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1847242	0.85	ALDH1A1 (0.49)	KMT2ASMN1; SMN2ALDH1A1KDM4EMEN1
	SCHEMBL4819554	0.82	GABRG2 (0.49)	KMT2ASMN1; SMN2ALDH1A1KDM4EMEN1
	SCHEMBL9791225	0.82	KMT2A (0.60)	KMT2ASMN1; SMN2ALDH1A1MEN1NPC1
	SCHEMBL30955930	0.81	FGFR1 (0.44)	KMT2ASMN1; SMN2ALDH1A1KDM4EMAPT
	SCHEMBL4816124	0.81	GABRG2 (0.47)	KMT2ASMN1; SMN2ALDH1A1KDM4EMEN1
	SCHEMBL832377	0.81	GABRG2 (0.44)	KMT2ASMN1; SMN2MEN1NPC1HPGD
	SCHEMBL7479053	0.81	HTR6 (0.44)	KMT2AALDH1A1KDM4EMEN1BCHE
	SCHEMBL832385	0.81	BRD4 (0.40)	KMT2AMEN1ASAH1HTTLMNA
	SCHEMBL1455275	0.81	HTR6 (0.47)	KMT2AMEN1HPGDBCHEFGFR1
	SCHEMBL482833	0.80	NR1H2 (0.43)	KMT2ASMN1; SMN2ALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 999 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.