SCHEMBL13559202

SCHEMBL13559202

N#C/C(=C\c1cc(O)c(/C=C(\C#N)S(=O)(=O)c2ccccc2)cc1O)S(=O)(=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.68
▸ HPGD P15428 6/20 0.68
▸ KMT2A Q03164 5/20 0.68
▸ KDM4E B2RXH2 5/20 0.68
▸ MEN1 O00255 4/20 0.68
▸ PKM P14618 3/20 0.68
▸ SMN1; SMN2 Q16637 3/20 0.68
▸ L3MBTL1 Q9Y468 2/20 0.68
▸ HSD17B10 Q99714 2/20 0.68
▸ POLB P06746 2/20 0.68
▸ GAA P10253 1/20 0.68
▸ ALPG P10696 1/20 0.68
▸ ALOX15 P16050 1/20 0.68
▸ ALOX12 P18054 1/20 0.68
▸ TDP1 Q9NUW8 1/20 0.68
▸ MAPT P10636 5/20 0.53
▸ LMNA P02545 4/20 0.53
▸ MAPK1 P28482 2/20 0.53
▸ CASP1 P29466 1/20 0.53
▸ CASP7 P55210 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7951896 0.81 ALDH1A1 (1.00) ALDH1A1HPGDKMT2AKDM4EMEN1
SCHEMBL7964130 0.81 ALDH1A1 (1.00) ALDH1A1HPGDKMT2AKDM4EMEN1
SCHEMBL7964126 0.81 ALDH1A1 (1.00) ALDH1A1HPGDKMT2AKDM4EMEN1
SCHEMBL4909621 0.80 PKM (0.79) ALDH1A1HPGDKMT2AKDM4EMEN1
SCHEMBL4909612 0.80 PKM (0.79) ALDH1A1HPGDKMT2AKDM4EMEN1
SCHEMBL4912425 0.80 PKM (0.79) ALDH1A1HPGDKMT2AKDM4EMEN1
SCHEMBL29289227 0.80 PKM (0.65) ALDH1A1HPGDKMT2AKDM4EMEN1
SCHEMBL29289223 0.80 PKM (0.65) ALDH1A1HPGDKMT2AKDM4EMEN1
SCHEMBL29289215 0.80 ALDH1A1 (0.58) ALDH1A1HPGDKMT2AKDM4EMEN1
SCHEMBL29289218 0.80 ALDH1A1 (0.58) ALDH1A1HPGDKMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012230-B2 Fluorescent nanoprobe for detecting hydrogen peroxide and fabrication method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-21 — — US disclosed
US-9012230-B2 Fluorescent nanoprobe for detecting hydrogen peroxide and fabrication method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-21 — — US disclosed
US-20120276651-A1 FLUORESCENT NANOPROBE FOR DETECTING HYDROGEN PEROXIDE AND FABRICATION METHOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-01 — — US disclosed
US-20120276651-A1 FLUORESCENT NANOPROBE FOR DETECTING HYDROGEN PEROXIDE AND FABRICATION METHOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120276651-A1 FLUORESCENT NANOPROBE FOR DETECTING HYDROGEN PEROXIDE AND FABRICATION METHOD THEREOF GPX4, PPOX, SQOR ALDH1A1 319/4885HPGD 89/4885KMT2A 3294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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