Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565780 | 0.87 | GRIA1 (0.46) | GRIA1NPY5RMTNR1AMTNR1BHTR1A | |
| SCHEMBL13565786 | 0.85 | THRB (0.46) | GRIA1NPY5RF2 | |
| SCHEMBL13565788 | 0.85 | GRIA1 (0.44) | GRIA1NPY5RMTNR1AMTNR1BHTR1A | |
| SCHEMBL13565422 | 0.84 | MTNR1A (0.40) | NPY5RMTNR1AMTNR1BDRD2DRD4 | |
| SCHEMBL12882395 | 0.84 | ALDH1A1 (0.46) | HTR1A | |
| SCHEMBL17090498 | 0.83 | PKM (0.47) | GRIA1NPY5RMTNR1AMTNR1BHTR1A | |
| SCHEMBL13565022 | 0.83 | GRIA1 (0.42) | GRIA1NPY5RMTNR1AMTNR1BHTR1A | |
| SCHEMBL13564798 | 0.82 | GRIA1 (0.46) | GRIA1NPY5RMTNR1AMTNR1BHTR1A | |
| SCHEMBL17090496 | 0.82 | KMT2A (0.48) | GRIA1NPY5RMTNR1AMTNR1BHTR1A | |
| SCHEMBL11935831 | 0.82 | DUT (0.42) | GRIA1NPY5RMTNR1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |