Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 10/20 | 0.55 |
| ▸ | CA12 | O43570 | 9/20 | 0.55 |
| ▸ | CA1 | P00915 | 9/20 | 0.55 |
| ▸ | CA9 | Q16790 | 6/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 5/20 | 0.48 |
| ▸ | CA5A | P35218 | 5/20 | 0.48 |
| ▸ | CA7 | P43166 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23590718 | 1.00 | CYP2D6 (0.57) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL23590717 | 1.00 | CYP2D6 (0.57) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL21021361 | 1.00 | CYP2D6 (0.57) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL10147769 | 0.98 | THRB (0.55) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL10147765 | 0.91 | THRB (0.49) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL10147759 | 0.91 | THRB (0.49) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL10147743 | 0.91 | THRB (0.48) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL14003596 | 0.88 | CYP2D6 (0.45) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL19782347 | 0.87 | CYP2D6 (0.59) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL12113494 | 0.87 | CYP2D6 (0.47) | CYP2D6THRBHSD17B10TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293701-A1 | LIGAND COMPOUNDS, CONJUGATES, AND APPLICATIONS THEREOF | ARGORNA PHARMACEUTICALS CO., LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| US-20220041641-A1 | QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION | SENDA BIOSCIENCES INC (US) | 2022-02-10 | — | — | US | disclosed |
| US-20200369703-A1 | Modified oligonucleotides and compound that can be used for synthesizing same | GUANGZHOU RIBOBIO CO LTD (CN) | 2020-11-26 | — | — | US | disclosed |
| EP-3564239-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | Shenzhen Immunova Pharmaceutical Co., Ltd. (CN) | 2019-11-06 | — | — | EP | disclosed |
| US-9120814-B2 | Compounds with embedded benzopyran motif for core structures and preparation method thereof | SNU R&DB FOUNDATION (KR) | 2015-09-01 | — | — | US | disclosed |
| US-20090326015-A1 | COMPOUNDS WITH EMBEDDED BENZOPYRAN MOTIF FOR CORE STRUCTURES AND PREPARATION METHOD THEREOF | SNU R&DB FOUNDATION (KR) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041641-A1 | QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION | SLC10A2, SLC10A1, BCAT2 | CYP2D6 2975/4885THRB 1472/4885HSD17B10 2003/4885 |
| US-20090326015-A1 | COMPOUNDS WITH EMBEDDED BENZOPYRAN MOTIF FOR CORE STRUCTURES AND PREPARATION METHOD THEREOF | BCR, HCCS, YBX3 | CYP2D6 287/4885THRB 4798/4885HSD17B10 3181/4885 |
| US-20200369703-A1 | Modified oligonucleotides and compound that can be used for synthesizing same | POLRMT, RNASE1, ADAR | CYP2D6 3340/4885THRB 4067/4885HSD17B10 2906/4885 |
| US-20230293701-A1 | LIGAND COMPOUNDS, CONJUGATES, AND APPLICATIONS THEREOF | ASGR1, HAVCR2, SLC10A1 | CYP2D6 1274/4885THRB 1331/4885HSD17B10 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.