Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044722 | 0.86 | ALOX5 (0.60) | ALOX5HTR2AGAAALDH1A1HTR2C | |
| SCHEMBL3034608 | 0.81 | CCR5 (0.53) | ALOX5HTR2AGAAALDH1A1HTR2C | |
| SCHEMBL17285933 | 0.78 | SIGMAR1 (0.57) | HTR2AGAAALDH1A1HTR2CL3MBTL1 | |
| SCHEMBL3604727 | 0.74 | C5AR1 (0.60) | SIGMAR1CCR5C5AR1 | |
| SCHEMBL13580709 | 0.74 | SIGMAR1 (0.47) | L3MBTL1SIGMAR1HRH3 | |
| SCHEMBL3046877 | 0.71 | CCR5 (0.54) | ALDH1A1CHRM5CHRM1CHRM3CYP1A2 | |
| SCHEMBL3038919 | 0.71 | LMNA (0.46) | HTR2AHTR2CL3MBTL1CHRM5CHRM1 | |
| SCHEMBL15088420 | 0.70 | MCHR1 (0.67) | HTR2AGAAALDH1A1HTR2CL3MBTL1 | |
| SCHEMBL3038901 | 0.70 | RAB9A (0.60) | HTR2AGAAALDH1A1HTR2CL3MBTL1 | |
| SCHEMBL10261038 | 0.69 | MAOB (0.66) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434765-B1 | SUBSTITUTED PIPERIDINES WITH SELECTIVE BINDING TO HISTAMINE H3-RECEPTOR | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-12-02 | — | — | EP | disclosed |