Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 6/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766903 | 0.88 | RAD51 (0.46) | RAD51ALDH1A1SMN1; SMN2MAOBTGM2 | |
| SCHEMBL12994621 | 0.81 | TGM2 (0.59) | ALDH1A1SMN1; SMN2TGM2TDP1NPC1 | |
| SCHEMBL4153167 | 0.81 | TGM2 (0.57) | RAD51ALDH1A1SMN1; SMN2PLAUTGM2 | |
| SCHEMBL3797430 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL14301433 | 0.78 | RAB9A (0.52) | ALDH1A1SMN1; SMN2MAOBTGM2F13A1 | |
| SCHEMBL1672145 | 0.77 | CYP17A1 (0.49) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8207530 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL8766519 | 0.77 | RXFP1 (0.54) | RAD51ALDH1A1SMN1; SMN2PLAUTGM2 | |
| SCHEMBL1877254 | 0.76 | ALDH1A1 (0.48) | RAD51ALDH1A1MAOBTGM2F13A1 | |
| SCHEMBL8867476 | 0.76 | THRA (0.42) | ALDH1A1SMN1; SMN2PLAUTGM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1258568-C | Polymer composition and its use | BAUSCH & LOMB (US) | 2006-06-07 | — | — | CN | claimed |
| CN-1270973-A | Polymer composition and its use | BAUSCH & LOMB (US) | 2000-10-25 | — | — | CN | claimed |
| US-5449729-A | Vinyl monomer and crosslinking agent and acrylates with styrene | BAUSCH & LOMB INCORPORATED (US) | 1995-09-12 | — | — | US | claimed |
| EP-0611367-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. | BAUSCH & LOMB (US) | 1994-08-24 | — | — | EP | claimed |
| US-5310779-A | Compatible crosslinkers having vinyl-, acrylic-and/or styrenyl-groups to crosslink incompatible unsaturated addition monomers; contact lens; molding materials | BAUSCH & LOMB INCORPORATED (US) | 1994-05-10 | — | — | US | claimed |
| CN-1074457-A | Novel crosslinking agent capable of being cured by ultraviolet rays for copolymerization | BAUSCH & LOMB (US) | 1993-07-21 | — | — | CN | claimed |
| WO-1993009084-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | claimed |
| CN-1258568-C | Polymer composition and its use | BAUSCH & LOMB (US) | 2006-06-07 | — | — | CN | disclosed |
| CN-1063764-C | Process for preparing polymers | BAUSCH & LOMB (US) | 2001-03-28 | — | — | CN | disclosed |
| CN-1270973-A | Polymer composition and its use | BAUSCH & LOMB (US) | 2000-10-25 | — | — | CN | disclosed |
| EP-0611367-B1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB (US) | 1997-06-25 | — | — | EP | disclosed |
| US-5512205-A | BIOMEDICAL ARTICLES, CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1996-04-30 | — | — | US | disclosed |
| US-5310779-A | Compatible crosslinkers having vinyl-, acrylic-and/or styrenyl-groups to crosslink incompatible unsaturated addition monomers; contact lens; molding materials | BAUSCH & LOMB INCORPORATED (US) | 1994-05-10 | — | — | US | disclosed |
| CN-1074457-A | Novel crosslinking agent capable of being cured by ultraviolet rays for copolymerization | BAUSCH & LOMB (US) | 1993-07-21 | — | — | CN | disclosed |
| WO-1993009084-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | disclosed |