SCHEMBL4153167

SCHEMBL4153167

C=COC(=O)Nc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 2/20 0.57
▸ SMN1; SMN2 Q16637 6/20 0.50
▸ TSHR P16473 2/20 0.50
▸ TP53 P04637 1/20 0.50
▸ EPHX1 P07099 1/20 0.50
▸ EPHX2 P34913 1/20 0.50
▸ CDK9 P50750 1/20 0.50
▸ CLK4 Q9HAZ1 1/20 0.50
▸ ALDH1A1 P00352 2/20 0.47
▸ GAA P10253 2/20 0.47
▸ HTT P42858 1/20 0.47
▸ NAPRT Q6XQN6 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ RAB9A P51151 3/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ NPC1 O15118 2/20 0.46
▸ MAPT P10636 1/20 0.46
▸ RAD51 Q06609 1/20 0.46
▸ RECQL P46063 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10444074 0.86 TGM2 (0.55) TGM2SMN1; SMN2TSHRTP53EPHX1
SCHEMBL3799021 0.86 RAB9A (0.57) SMN1; SMN2ALDH1A1HTTRAB9AMEN1
SCHEMBL28219382 0.82 SMN1; SMN2 (0.52) TGM2SMN1; SMN2TSHRTP53EPHX1
SCHEMBL13586723 0.81 CYP19A1 (0.44) TGM2SMN1; SMN2ALDH1A1GAARAB9A
SCHEMBL12994621 0.81 TGM2 (0.59) TGM2SMN1; SMN2ALDH1A1RAB9AMEN1
SCHEMBL8767860 0.81 RAD51 (0.44) TGM2SMN1; SMN2ALDH1A1RAB9AMEN1
SCHEMBL482921 0.80 NAPRT (0.52) TGM2SMN1; SMN2TSHRTP53EPHX1
SCHEMBL12994614 0.79 HSD17B10 (0.57) SMN1; SMN2TP53ALDH1A1HSD17B10RAB9A
SCHEMBL3797430 0.78 ALDH1A1 (0.53) SMN1; SMN2TP53ALDH1A1GAAHTT
SCHEMBL514783 0.77 SMN1; SMN2 (0.56) TGM2SMN1; SMN2TSHRTP53EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111171210-A Tetrafluoroethylene-alkenyl carbamate-perfluoroalkyl vinyl ether dispersion resin and microporous membrane prepared therefrom 苏州世华新材料科技股份有限公司 2020-05-19 — — CN claimed
US-6288141-B1 Ink compositions XEROX CORPORATION 2001-09-11 — — US claimed
CN-111171210-A Tetrafluoroethylene-alkenyl carbamate-perfluoroalkyl vinyl ether dispersion resin and microporous membrane prepared therefrom 苏州世华新材料科技股份有限公司 2020-05-19 — — CN disclosed
US-9527617-B2 Packaging solutions BAUSCH & LOMB INCORPORATED (US) 2016-12-27 — — US disclosed
US-20130276407-A1 Packaging Solutions SANTARUS, INC. 2013-10-24 — — US disclosed
US-8490782-B2 Packaging solutions BAUSCH & LOMB INCORPORATED (US) 2013-07-23 — — US disclosed
WO-2009067313-A1 PACKAGING SOLUTIONS BAUSCH & LOMB INCORPORATED (US) 2009-05-28 — — WO disclosed
US-20090126318-A1 Packaging Solutions RASTOGI SANJAY M 2009-05-21 — — US disclosed
US-20090100801-A1 Packaging Solutions BAUSCH & LOMB INCORPORATED (US) 2009-04-23 — — US disclosed
US-20020151740-A1 Synthesis of vinyl carbonates for use in producing vinyl carbamates ALLEN DAVID LEWIS (US) 2002-10-17 — — US disclosed
US-6423862-B1 REACTING HALOFORMIC ACID DERIVATIVE WITH ALKALI METAL FLUORIDE IN PRESENCE OF PHASE TRANSFER CATALYST; REACTING PRODUCT WITH VINYL SILOXANE COMPOUND TO FORM VINYL CARBONATE DERIVATIVE WRIGHT CHEMICAL CORPORATION 2002-07-23 — — US disclosed
US-20020058829-A1 SYNTHESIS OF VINYL CARBONATES FOR USE IN PRODUCING VINYL CARBAMATES ALLEN DAVID LEWIS (US) 2002-05-16 — — US disclosed
US-6362363-B1 REACTING HALOFORMIC ACID, ALKALI METAL FLUORIDE, A VINYLOXYSILANE, AND AN AMINE; PHASE TRANSFER AGENTS WRIGHT CHEMICAL CORPORATION 2002-03-26 — — US disclosed
US-6288141-B1 Ink compositions XEROX CORPORATION 2001-09-11 — — US disclosed
US-6284911-B1 FLUORINATING A HALOFORMATE WITH A IA METAL FLUORIDE IN THE PRESENCE OF A PHASE TRANSFER CATALYST AND A SOLVENT; ESTERIFIFYING PRODUCT WITH A TRIHYDROCARBYL(VINYLOXY)SILANE WRIGHT CHEMICAL CORPORATION 2001-09-04 — — US disclosed
WO-2001000634-A1 SYNTHESIS OF VINYL CARBONATES FOR USE IN PRODUCING VINYL CARBAMATES WRIGHT CHEMICAL CORPORATION (US) 2001-01-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058829-A1 SYNTHESIS OF VINYL CARBONATES FOR USE IN PRODUCING VINYL CARBAMATES F12, F11, ME1 TGM2 2897/4885SMN1; SMN2 3305/4885TSHR 1970/4885
US-20020151740-A1 Synthesis of vinyl carbonates for use in producing vinyl carbamates F12, F11, ME1 TGM2 2897/4885SMN1; SMN2 3305/4885TSHR 1970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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