Water

Water

SCHEMBL1358864

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nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL1898764 1.00
Water SCHEMBL27362890 1.00
Water SCHEMBL1598810 1.00
Water SCHEMBL1599688 0.87
Water SCHEMBL28154539 0.87
Fluoride SCHEMBL23456586 0.87
Water SCHEMBL23456636 0.87
Water SCHEMBL22634203 0.87
Water SCHEMBL20959670 0.87
Water SCHEMBL27736166 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111777497-B Method for preparing 4-oxo-isophorone by catalytic oxidation of beta-isophorone 万华化学集团股份有限公司 2022-07-12 CN claimed
CN-111777497-A Method for preparing 4-oxo-isophorone by catalytic oxidation of beta-isophorone 万华化学集团股份有限公司 2020-10-16 CN claimed
US-8932887-B2 Method for manufacturing LED with transparent ceramics BRIGHT CRYSTALS TECHNOLOGY, INC. (CN) 2015-01-13 US claimed
CN-102272075-B Method of impregnating crucibles and refractory articles ZIRCOA INC 2013-08-28 CN claimed
CN-102272075-A Method of impregnating crucibles and refractory articles 2011-12-07 CN claimed
CN-118320730-A Reaction device and method for synthesizing tea-flavored ketone 山东富宇石化有限公司 2024-07-12 CN disclosed
CN-111777497-B Method for preparing 4-oxo-isophorone by catalytic oxidation of beta-isophorone 万华化学集团股份有限公司 2022-07-12 CN disclosed
CN-111777497-B Method for preparing 4-oxo-isophorone by catalytic oxidation of beta-isophorone 万华化学集团股份有限公司 2022-07-12 CN disclosed
CN-114436327-A Zirconium dioxide nanometer hollow wire, preparation method thereof and heat insulation felt 中国建筑材料科学研究总院有限公司 2022-05-06 CN disclosed
CN-111777497-A Method for preparing 4-oxo-isophorone by catalytic oxidation of beta-isophorone 万华化学集团股份有限公司 2020-10-16 CN disclosed
CN-111777497-A Method for preparing 4-oxo-isophorone by catalytic oxidation of beta-isophorone 万华化学集团股份有限公司 2020-10-16 CN disclosed
EP-2865655-B1 Refractory materials CORNING INC (US) 2017-07-26 EP disclosed
WO-2006073841-A9 REFRACTORY MATERIALS CORNING INC (US) 2006-10-12 WO disclosed
WO-2006073841-A1 REFRACTORY MATERIALS CORNING INCORPORATED (US) 2006-07-13 WO disclosed
CN-1636939-A Method of deagglomerating ceramic powder, deagglomeration mill used therefor and method of preparing highly dispersed slurry using the deagglomerated powder SAMSUNG ELECTRO MECH (KR) 2005-07-13 CN disclosed
CN-1069846-C Sol-gel method for preparing yttrium oxide blended zirconium oxide ceramic micro filter film CHINA SCI & TECH UNIV (CN) 2001-08-22 CN disclosed
CN-1109381-A Sol-gel method for preparing yttrium oxide blended zirconium oxide ceramic micro filter film CHINA SCIENCE AND TECHNIC UNIV (CN) 1995-10-04 CN disclosed
EP-0422665-B1 Air/fuel ratio sensor NGK SPARK PLUG CO (JP) 1995-08-23 EP disclosed
US-5174885-A Quick response, stable limiting current even in atmosphere including no oxides NGK SPARK PLUG CO. LTD. (JP) 1992-12-29 US disclosed
EP-0422665-A2 Air/fuel ratio sensor NGK Spark Plug Co. Ltd. (JP) 1991-04-17 EP disclosed