Water

Water

SCHEMBL1898764

O.O.[Y].[Zr]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27362890 1.00
Water SCHEMBL1358864 1.00
Water SCHEMBL1598810 1.00
Water SCHEMBL1599688 0.87
Water SCHEMBL28154539 0.87
Fluoride SCHEMBL23456586 0.87
Water SCHEMBL23456636 0.87
Water SCHEMBL22634203 0.87
Water SCHEMBL20959670 0.87
Water SCHEMBL27736166 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110344024-A Zone controlled rare earth oxide ALD and CVD coatings 应用材料公司 2019-10-18 CN claimed
CN-106747433-A Zirconium oxide-based nano ceramic tool die material and preparation method thereof 安徽拓吉泰新型陶瓷科技有限公司 2017-05-31 CN claimed
EP-0230554-B1 HIGH-TEMPERATURE PROTECTIVE LAYER AND METHOD OF MANUFACTURING THE SAME Asea Brown Boveri Aktiengesellschaft (DE) 1991-03-06 EP claimed
CN-119274717-A Potential function construction method of complex-phase zirconia ceramic 哈尔滨工业大学 2025-01-07 CN disclosed
CN-118477667-A High-activity high-selectivity CO2Co-based intermetallic carbide catalyst for preparing methanol by hydrogenation and preparation method and application thereof 浙江工业大学 2024-08-13 CN disclosed
CN-114672787-B Zone controlled rare earth oxide ALD and CVD coatings 应用材料公司 2024-02-23 CN disclosed
CN-115701642-A Ceramic electronic device, dielectric material, and method for manufacturing ceramic electronic device 太阳诱电株式会社 2023-02-10 CN disclosed
CN-110344024-A Zone controlled rare earth oxide ALD and CVD coatings 应用材料公司 2019-10-18 CN disclosed
CN-109678500-A Yttrium stable zirconium oxide ceramic powders and its preparation method and application 广州德隆宝环保科技有限公司 2019-04-26 CN disclosed
CN-108352316-A Etch reactants and use its oxide etch processes without plasma 乔治洛德方法研究和开发液化空气有限公司 2018-07-31 CN disclosed
CN-104122303-B A kind of measure the sensor of nitrogen oxides total amount in gaseous mixture 中国第汽车股份有限公司 2016-09-21 CN disclosed
US-9057128-B2 Multiple level showerhead design APPLIED MATERIALS, INC. (US) 2015-06-16 US disclosed
CN-102499900-B Phosphate glass-infiltrated ZrO2 ceramic dental material and preparation method thereof UNIV DONGHUA 2013-01-16 CN disclosed
WO-2012128789-A1 MULTIPLE LEVEL SHOWERHEAD DESIGN APPLIED MATERIALS, INC. (US) 2012-09-27 WO disclosed
US-20120234945-A1 MULTIPLE LEVEL SHOWERHEAD DESIGN APPLIED MATERIALS, INC. (US) 2012-09-20 US disclosed
CN-102499900-A Phosphate glass-infiltrated ZrO2 ceramic dental material and preparation method thereof UNIV DONGHUA 2012-06-20 CN disclosed
CN-201884269-U Valve ball for advanced ceramic oil well pump YONGLI YANG 2011-06-29 CN disclosed
EP-2318313-A1 FLUIDIZED BED REACTOR FOR PRODUCTION OF HIGH PURITY SILICON Siliken Chemicals S.L. (ES) 2011-05-11 EP disclosed
US-4347113-A COATED PLATINUM-RHODIUM ALLOY ELECTRODE AND AN UNCOATED PALLADIUM-NOBLE METAL ALLOY REFERENCE ELECTRODE ROBERT BOSCH GMBH (DE) 1982-08-31 US disclosed