Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 8/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 5/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1108498 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP13 | |
| SCHEMBL13209004 | 0.75 | LMNA (0.48) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP13 | |
| SCHEMBL13209012 | 0.75 | LMNA (0.48) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP13 | |
| SCHEMBL542612 | 0.75 | LMNA (0.48) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP13 | |
| SCHEMBL12405620 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP13 | |
| SCHEMBL8342071 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP13 | |
| SCHEMBL13209009 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP13 | |
| SCHEMBL15427305 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP13 | |
| SCHEMBL31676820 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP13 | |
| SCHEMBL1132700 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025226892-A1 | SPIROCYCLE-CONTAINING DIAMINOMETHYLENE PYRIMIDINE-2,4,6-TRIONE AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS | SEPTERNA, INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| US-8729096-B2 | Imidazolidine-2,4-dione derivatives as N-formyl peptide receptor 2 modulators | ALLERGAN, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-20130217720-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR 2 MODULATORS | ALLERGAN, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| US-8173697-B2 | Alkoxyalkyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173697-B2 | Alkoxyalkyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173697-B2 | Alkoxyalkyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8067458-B2 | Alkoxyalkyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-8067458-B2 | Alkoxyalkyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-8067458-B2 | Alkoxyalkyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20090298828-A1 | Alkoxyalkyl-Substituted Cyclic Keto-Enols | BAYER CROPSCIENCE AG (DE) | 2009-12-03 | — | — | US | disclosed |
| US-20090298828-A1 | Alkoxyalkyl-Substituted Cyclic Keto-Enols | BAYER CROPSCIENCE AG (DE) | 2009-12-03 | — | — | US | disclosed |
| US-20090239906-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-09-24 | — | — | US | disclosed |
| US-20090239906-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-09-24 | — | — | US | disclosed |
| US-20090239906-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-09-24 | — | — | US | disclosed |
| EP-2029531-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETO-ENOLS | Bayer CropScience AG (DE) | 2009-03-04 | — | — | EP | disclosed |
| EP-2013168-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007140881-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETO-ENOLS | BAYER CROPSCIENCE AG (DE) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007140881-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETO-ENOLS | BAYER CROPSCIENCE AG (DE) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007121868-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007121868-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (US) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298828-A1 | Alkoxyalkyl-Substituted Cyclic Keto-Enols | DDT, AKR1D1, EBP | SMN1; SMN2 4868/4885NPSR1 3151/4885ALDH1A1 2870/4885 |
| US-20130217720-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR 2 MODULATORS | FPR2, FPR1, FPR3 | SMN1; SMN2 3872/4885NPSR1 54/4885ALDH1A1 4657/4885 |
| US-20090239906-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | DDT, EBP, TET1 | SMN1; SMN2 4870/4885NPSR1 2825/4885ALDH1A1 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.