Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8259120 | 0.90 | HPGD (0.49) | ALDH1A1HPGDMAPTSMN1; SMN2KMT2A | |
| SCHEMBL13601370 | 0.87 | NAAA (0.50) | HPGDMAPT | |
| SCHEMBL2663390 | 0.86 | MAPT (0.48) | ALDH1A1MAPTSMN1; SMN2HTTRAB9A | |
| SCHEMBL13601455 | 0.83 | POLB (0.51) | ALDH1A1SMN1; SMN2HTTPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL7585696 | 0.83 | GNAI3 (0.44) | ALDH1A1SMN1; SMN2POLBKMT2AKDM4E | |
| SCHEMBL13601372 | 0.82 | CHRM2 (0.41) | ALDH1A1HPGDMAPTSMN1; SMN2HTT | |
| SCHEMBL12773957 | 0.82 | GNAI3 (0.45) | ALDH1A1SMN1; SMN2POLBKMT2AKDM4E | |
| SCHEMBL22281964 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTSMN1; SMN2HTT | |
| SCHEMBL13601375 | 0.80 | NPC1 (0.39) | ALDH1A1HPGDSMN1; SMN2POLBKMT2A | |
| SCHEMBL10928073 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625886-B2 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-01 | — | — | US | disclosed |
| US-7625886-B2 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-01 | — | — | US | disclosed |
| US-7332489-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |
| US-7268134-B2 | Medical devices employing triazine compounds and compositions thereof | REDDY US THERAPEUTICS, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-7268134-B2 | Medical devices employing triazine compounds and compositions thereof | REDDY US THERAPEUTICS, INC. (US) | 2007-09-11 | — | — | US | disclosed |