Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28646996 | 0.84 | TSHR (0.35) | TSHRUSP2AKT1THRBCYP1A2 | |
| SCHEMBL14217890 | 0.82 | ALDH1A1 (0.40) | TSHRUSP2AKT1THRBHDAC3 | |
| SCHEMBL25682469 | 0.75 | L3MBTL1 (0.34) | TSHRUSP2AKT1THRBPOLB | |
| SCHEMBL964946 | 0.72 | DNMT1 (0.44) | TP53HSD17B10POLBALDH1A1CYP1A2 | |
| SCHEMBL11975541 | 0.72 | MGLL (0.38) | TP53ALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL5161621 | 0.71 | ALDH1A1 (0.42) | TP53ALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL20887626 | 0.71 | PKM (0.33) | TSHRALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL23805314 | 0.71 | HDAC3 (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6567846 | 0.71 | LMNA (0.47) | TP53POLBALDH1A1CYP1A2HPGD | |
| SCHEMBL21648874 | 0.70 | ANPEP (0.44) | THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325262-A1 | Immobilization of biological molecules onto surfaces coated with monolayers | SURFACE LOGIX, INC. | 2009-12-31 | — | — | US | disclosed |
| US-7439056-B2 | Peelable and resealable devices for arraying materials | SURFACE LOGIX INC. (US) | 2008-10-21 | — | — | US | disclosed |
| US-7351575-B2 | Methods for processing biological materials using peelable and resealable devices | SURFACE LOGIX, INC. (US) | 2008-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325262-A1 | Immobilization of biological molecules onto surfaces coated with monolayers | EPCAM, ICAM1, MB | TSHR 887/4885USP2 1131/4885AKT1 4538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.