Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13610484 | 0.84 | TSHR (0.35) | TSHRUSP2AKT1CYP1A2THRB | |
| SCHEMBL14217890 | 0.82 | ALDH1A1 (0.40) | TSHRUSP2AKT1GAANFKB1 | |
| SCHEMBL25682469 | 0.81 | L3MBTL1 (0.34) | TSHRUSP2AKT1DPP7RRM1 | |
| SCHEMBL17841877 | 0.81 | TERT (0.40) | TSHRTERTAKT1GAAGPR88 | |
| SCHEMBL30269173 | 0.81 | TERT (0.40) | TSHRTERTAKT1GAAGPR88 | |
| SCHEMBL20887626 | 0.78 | PKM (0.33) | TSHRCYP1A2 | |
| SCHEMBL22134518 | 0.77 | TSHR (0.40) | TSHRUSP2TERTDPP7GAA | |
| SCHEMBL21648874 | 0.76 | ANPEP (0.44) | THRBL3MBTL1 | |
| SCHEMBL19302564 | 0.76 | TERT (0.31) | TERTAKT1 | |
| SCHEMBL31087110 | 0.75 | GNAI3 (0.40) | GRIA1TLR2SIRT6SIRT1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116059390-A | Prodrugs of cytotoxic actives with enzymatically cleavable groups | 拜耳制药股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-114917361-A | Antibody Drug Conjugates (ADC) and antibody prodrug conjugates (APDC) with enzyme cleavable groups | 拜耳医药股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-107635586-B | Antibody-drug conjugates (ADC) of KSP inhibitors with aglycosylated anti-TWEAKR antibodies | 拜耳医药股份有限公司 | 2021-09-24 | — | — | CN | disclosed |