Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612035 | 0.88 | MAPT (0.41) | DPP4CNR1 | |
| SCHEMBL13612028 | 0.84 | MEN1 (0.36) | DPP4DPP8ALDH1A1EPHX2 | |
| SCHEMBL13612038 | 0.82 | KMT2A (0.41) | DPP4CNR1ATMALDH1A1CHRM4 | |
| SCHEMBL13612023 | 0.81 | ALDH1A1 (0.38) | DPP4DPP8DPP9ALDH1A1GLA | |
| SCHEMBL13611902 | 0.80 | DPP4 (0.46) | DPP4DPP8DPP9CNR1EPHX2 | |
| SCHEMBL13612014 | 0.80 | MAPT (0.40) | DPP4DPP8DPP9CNR1ALDH1A1 | |
| SCHEMBL13612016 | 0.79 | DPP4 (0.44) | DPP4DPP8DPP9CNR1RAB9A | |
| SCHEMBL13611869 | 0.75 | DPP4 (0.36) | DPP4DPP8DPP9 | |
| SCHEMBL13612007 | 0.75 | DPP4 (0.35) | DPP4DPP8DPP9TAAR1CYP3A4 | |
| SCHEMBL13612018 | 0.73 | DPP4 (0.50) | DPP4DPP8DPP9CNR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635699-B2 | Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-12-22 | — | — | US | disclosed |