Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611767 | 0.88 | TDP1 (0.38) | CNR1DPP4 | |
| SCHEMBL13612049 | 0.85 | ANO1 (0.40) | MAPTKMT2AMEN1DPP4LMNA | |
| SCHEMBL13612028 | 0.83 | MEN1 (0.36) | MAPTPOLBTP53KMT2AMEN1 | |
| SCHEMBL13611902 | 0.80 | DPP4 (0.46) | CNR1DPP4CNR2 | |
| SCHEMBL13612014 | 0.80 | MAPT (0.40) | MAPTPOLBCNR1KMT2AMEN1 | |
| SCHEMBL13612023 | 0.80 | ALDH1A1 (0.38) | MAPTTP53KMT2AMEN1DPP4 | |
| SCHEMBL13612016 | 0.79 | DPP4 (0.44) | CNR1KMT2AMEN1DPP4CNR2 | |
| SCHEMBL13611869 | 0.76 | DPP4 (0.36) | MAPTDPP4 | |
| SCHEMBL13612018 | 0.74 | DPP4 (0.50) | CNR1DPP4CNR2 | |
| SCHEMBL13612007 | 0.73 | DPP4 (0.35) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635699-B2 | Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-12-22 | — | — | US | disclosed |