Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 5/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612016 | 0.84 | DPP4 (0.44) | DPP4DPP8DPP9CNR1NPC1 | |
| SCHEMBL13612028 | 0.81 | MEN1 (0.36) | MAPTKDM4EDPP4DPP8POLB | |
| SCHEMBL13611869 | 0.81 | DPP4 (0.36) | MAPTKDM4EDPP4DPP8DPP9 | |
| SCHEMBL13611902 | 0.80 | DPP4 (0.46) | DPP4DPP8DPP9CNR1NPC1 | |
| SCHEMBL13612035 | 0.80 | MAPT (0.41) | MAPTDPP4CNR1POLBMEN1 | |
| SCHEMBL13612023 | 0.80 | ALDH1A1 (0.38) | MAPTKDM4EDPP4DPP8DPP9 | |
| SCHEMBL13611767 | 0.80 | TDP1 (0.38) | DPP4DPP8DPP9CNR1RAB9A | |
| SCHEMBL13612029 | 0.79 | DPP4 (0.48) | DPP4DPP8DPP9MEN1KMT2A | |
| SCHEMBL13612049 | 0.79 | ANO1 (0.40) | MAPTDPP4DPP8DPP9TSHR | |
| SCHEMBL13612018 | 0.77 | DPP4 (0.50) | DPP4DPP8DPP9CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635699-B2 | Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-12-22 | — | — | US | disclosed |