Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611864 | 0.90 | DPP4 (0.40) | DPP4CYP3A4CYP2C19DPP8DPP9 | |
| SCHEMBL13612028 | 0.78 | MEN1 (0.36) | DPP4DPP8 | |
| SCHEMBL13612014 | 0.76 | MAPT (0.40) | DPP4DPP8DPP9 | |
| SCHEMBL13612016 | 0.76 | DPP4 (0.44) | DPP4DPP8DPP9 | |
| SCHEMBL13611767 | 0.75 | TDP1 (0.38) | DPP4CYP3A4CYP2C19DPP8DPP9 | |
| SCHEMBL13612038 | 0.74 | KMT2A (0.41) | DPP4CYP3A4CYP2C19 | |
| SCHEMBL13612023 | 0.73 | ALDH1A1 (0.38) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL13612035 | 0.73 | MAPT (0.41) | DPP4 | |
| SCHEMBL13612049 | 0.72 | ANO1 (0.40) | DPP4CYP3A4CYP2C19DPP8DPP9 | |
| SCHEMBL13611869 | 0.72 | DPP4 (0.36) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635699-B2 | Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-12-22 | — | — | US | disclosed |