Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612016 | 0.89 | DPP4 (0.44) | DPP4DPP8DPP9 | |
| SCHEMBL13612018 | 0.81 | DPP4 (0.50) | DPP4DPP8DPP9 | |
| SCHEMBL13612014 | 0.81 | MAPT (0.40) | DPP4DPP8DPP9KDM4EMAPT | |
| SCHEMBL13612029 | 0.79 | DPP4 (0.48) | DPP4DPP8DPP9 | |
| SCHEMBL13611879 | 0.79 | DPP4 (0.48) | DPP4DPP8DPP9 | |
| SCHEMBL13612028 | 0.77 | MEN1 (0.36) | DPP4DPP8KDM4EMAPT | |
| SCHEMBL13611902 | 0.76 | DPP4 (0.46) | DPP4DPP8DPP9 | |
| SCHEMBL13612035 | 0.76 | MAPT (0.41) | DPP4MAPT | |
| SCHEMBL13611767 | 0.75 | TDP1 (0.38) | DPP4DPP8DPP9 | |
| SCHEMBL13612023 | 0.74 | ALDH1A1 (0.38) | DPP4DPP8DPP9KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635699-B2 | Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-12-22 | — | — | US | disclosed |