SCHEMBL1361249

SCHEMBL1361249

CCCN1C(=O)NC(CS)C1=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 4/20 0.38
MMP9 P14780 4/20 0.38
MMP3 P08254 2/20 0.38
LMNA P02545 2/20 0.33
ABL1 P00519 2/20 0.33
RIN1 Q13671 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
GAA P10253 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
DHFR P00374 1/20 0.32
CYP19A1 P11511 1/20 0.32
PLA2G10 O15496 1/20 0.32
PLA2G5 P39877 1/20 0.32
POLB P06746 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1361115 0.89 MMP1 (0.46) MMP1MMP9MMP3ABL1RIN1
SCHEMBL4646184 0.89 MMP1 (0.46) MMP1MMP9MMP3ABL1RIN1
SCHEMBL1362950 0.83 LMNA (0.46) MMP1MMP9MMP3LMNATDP1
SCHEMBL1364257 0.78 LMNA (0.33) LMNAABL1RIN1TDP1GAA
SCHEMBL1362924 0.74 MEN1 (0.37) LMNAGAASMN1; SMN2CYP19A1POLB
SCHEMBL1362696 0.74 RIPK1 (0.42) MMP1MMP9MMP3GAASMN1; SMN2
SCHEMBL16001119 0.74 RIPK1 (0.42) MMP1MMP9MMP3GAASMN1; SMN2
SCHEMBL9186739 0.73 ALDH1A1 (0.44) LMNAABL1RIN1TDP1GAA
SCHEMBL11456944 0.73 ABL1 (0.41) ABL1RIN1TDP1GAASMN1; SMN2
SCHEMBL8724260 0.69 MEN1 (0.47) LMNAABL1RIN1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8066977-B2 Agent for permanent hair waving containing heterocyclic mercapto compound SHOWA DENKO K.K. (JP) 2011-11-29 US disclosed
EP-1883454-B1 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO KK (JP) 2009-11-04 EP disclosed
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound SHOWA DENKO K.K. (JP) 2009-08-20 US disclosed
EP-1883454-A2 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND Showa Denko K.K. (JP) 2008-02-06 EP disclosed
WO-2006126729-A2 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO K.K. (JP) 2006-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound NSD3, WNT3, MSRB3 MMP1 308/4885MMP9 1194/4885MMP3 379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.