Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452257 | 0.72 | ALDH1A1 (0.37) | HPGDALOX15SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29118467 | 0.70 | ALOX5 (0.46) | SMN1; SMN2LMNAALDH1A1RXFP1MAPT | |
| SCHEMBL29118494 | 0.69 | ALDH1A1 (0.40) | SMN1; SMN2LMNAALDH1A1RXFP1MAPT | |
| SCHEMBL10525830 | 0.68 | GAA (0.38) | HPGDSMN1; SMN2RAB9ALMNARXFP1 | |
| SCHEMBL29118472 | 0.68 | RPS6KA2 (0.46) | NPC1RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL4392928 | 0.67 | LMNA (0.39) | LMNAALDH1A1 | |
| SCHEMBL29118471 | 0.67 | PTGES (0.55) | NPC1RAB9ALMNAMAPT | |
| SCHEMBL13903712 | 0.66 | KCNA3 (0.38) | HPGDSMN1; SMN2NPC1LMNAKDM4E | |
| SCHEMBL13615126 | 0.66 | KMT2A (0.45) | HPGDSMN1; SMN2CYP1A2LMNAKDM4E | |
| SCHEMBL13903745 | 0.65 | KCNA3 (0.37) | HPGDSMN1; SMN2NPC1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141065-A2 | (1,2-BENZISOTHIAZOL-3-YL)(THIO)CARBAMATES AND (1,2-BENZISOTHIAZOL-3-YL)(THIO)OXAMATES AND THE OXIDATION FORMS THEREOF FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |
| EP-2123159-A1 | (1,2-Benzisothiazol-3-yl)(thio)carbamates and (1,2-Benzisothiazol-3-yl)(thio)oxamates and their oxidation forms as pesticides | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |