Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1079026 | 0.80 | SMN1; SMN2 (0.52) | MMESMN1; SMN2 | |
| SCHEMBL1078710 | 0.78 | MMP2 (0.42) | MMEADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8306045 | 0.76 | PIN1 (0.52) | MMEALOX15SMN1; SMN2MMP2 | |
| SCHEMBL1078750 | 0.75 | ADORA3 (0.39) | MMEADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL24019838 | 0.72 | ALOX15 (0.41) | ADORA3ADORA2AADORA2BADORA1ALOX15 | |
| SCHEMBL10869963 | 0.71 | PIN1 (0.39) | MMEADORA3ALOX15CCNCCDK8 | |
| SCHEMBL23849223 | 0.70 | MMP2 (0.44) | MMP2 | |
| SCHEMBL30889539 | 0.69 | HCAR3 (0.43) | MMEKDM5AHCAR3 | |
| SCHEMBL22901899 | 0.67 | SMN1; SMN2 (0.53) | ADORA3ADORA2AADORA2BADORA1XDH | |
| SCHEMBL2890259 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139834-A1 | BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | PONIARD PHARMACEUTICALS, INC. (US) | 2009-11-19 | — | — | WO | disclosed |