Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | CPB1 | P15086 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617217 | 0.75 | HDAC1 (0.39) | CPB2 | |
| SCHEMBL3838565 | 0.71 | SIGMAR1 (0.38) | CPB2MEN1KMT2ACPB1 | |
| SCHEMBL3838561 | 0.71 | SIGMAR1 (0.38) | CPB2MEN1KMT2ACPB1 | |
| SCHEMBL13617215 | 0.70 | ALDH1A1 (0.43) | DUTMEN1KMT2ATOP2ASMN1; SMN2 | |
| SCHEMBL13617430 | 0.69 | CPB2 (0.46) | CPB2DUTCPB1 | |
| SCHEMBL3841255 | 0.69 | CPB2 (0.64) | CPB2DUTCPB1 | |
| SCHEMBL3841800 | 0.64 | CPB2 (0.57) | CPB2DUTCPB1 | |
| SCHEMBL3839616 | 0.64 | CPB2 (0.57) | CPB2DUTCPB1 | |
| SCHEMBL3841237 | 0.64 | CPB2 (0.57) | CPB2DUTCPB1 | |
| SCHEMBL16427979 | 0.63 | LMNA (0.49) | DUTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311488-B1 | SUBSTITUTED IMIDAZOLES AS TAFIA INHIBITORS | PFIZER LTD (GB) | 2009-11-04 | — | — | EP | disclosed |