Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13412108 | 0.80 | SLC22A12 (0.46) | HTR6PTGES2MEN1KMT2A | |
| SCHEMBL13617879 | 0.78 | HTR6 (0.59) | HTR6POLBKMT2A | |
| SCHEMBL30737452 | 0.78 | ALDH1A1 (0.58) | HTR6ALDH1A1RECQLMEN1KMT2A | |
| SCHEMBL2068236 | 0.78 | ALDH1A1 (0.58) | HTR6ALDH1A1RECQLMEN1KMT2A | |
| SCHEMBL30737455 | 0.78 | PGR (0.52) | PTGES2POLBKMT2A | |
| SCHEMBL1260477 | 0.78 | PTGES2 (0.47) | HTR6PTGES2POLBALDH1A1PLAU | |
| SCHEMBL7901144 | 0.78 | KMT2A (0.62) | POLBALDH1A1MEN1KMT2A | |
| SCHEMBL30737349 | 0.78 | PGR (0.62) | PTGES2CCR2 | |
| SCHEMBL13617420 | 0.77 | HTR6 (0.66) | HTR6POLBPRMT1CYP19A1CCR2 | |
| Hydrochloric Acid SCHEMBL29885455 | 0.76 | ALDH1A1 (0.56) | HTR6ALDH1A1RECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817296-B1 | POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2009-11-04 | — | — | EP | disclosed |