Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tetrahydrofuran. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL4444183 | 1.00 | ALDH1A1 (0.80) | — | |
| Tetrahydrofuran SCHEMBL267714 | 1.00 | ALDH1A1 (0.80) | — | |
| Tetrahydrofuran SCHEMBL1005228 | 0.95 | ALDH1A1 (0.89) | — | |
| Tetrahydrofuran SCHEMBL1450115 | 0.90 | ALDH1A1 (0.80) | — | |
| Tetrahydrofuran SCHEMBL22129675 | 0.90 | ALDH1A1 (0.80) | — | |
| Tetrahydrofuran SCHEMBL6361564 | 0.90 | ALDH1A1 (0.80) | — | |
| Tetrahydrofuran SCHEMBL6345343 | 0.90 | ALDH1A1 (0.80) | — | |
| Tetrahydrofuran SCHEMBL22230565 | 0.90 | ALDH1A1 (0.80) | — | |
| Tetrahydrofuran SCHEMBL18729662 | 0.90 | — | — | |
| Tetrahydrofuran SCHEMBL4076453 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 572 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122032642-A | Ethylene tetramerization catalyst system without alkyl metal cocatalyst and preparation method and application thereof | 华东理工大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122032645-A | Ethylene selective oligomerization catalyst system with low solid byproduct generation, and preparation method and application thereof | 华东理工大学 | 2026-05-15 | — | — | CN | claimed |
| CN-119836425-A | Ligand compound, organic chromium compound, and catalyst composition comprising same | 株式会社LG化学 | 2025-04-15 | — | — | CN | claimed |
| CN-119657226-A | Catalyst composition and method for preparing 1-hexene by ethylene trimerization | 中国石油天然气股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-118290214-B | Method for preparing linear alpha-olefin by ethylene high-selectivity oligomerization | 广东众和工程设计有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119403812-A | Ligand compound, organic chromium compound, and catalyst composition containing same | 株式会社LG化学 | 2025-02-07 | — | — | CN | claimed |
| CN-119365472-A | Ligand compound, organic chromium compound, and catalyst composition comprising same | 株式会社LG化学 | 2025-01-24 | — | — | CN | claimed |
| CN-119173521-A | Ligand compound, organic chromium compound, and catalyst composition comprising same | 株式会社LG化学 | 2024-12-20 | — | — | CN | claimed |
| CN-114409495-B | Ethylene tetramerization method | 中国石油天然气股份有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-116328832-B | Organic polymer carrier, main catalyst, ethylene polymerization catalyst composition and application thereof | 中国石油化工股份有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-106492880-A | A kind of catalyst for ethylene oligomerization and preparation method thereof | 天津科技大学 | 2017-03-15 | — | — | CN | claimed |
| US-20170029346-A1 | LIGAND COMPOUND, ORGANIC CHROMIUM COMPOUND, CATALYST SYSTEM FOR OLIGOMERIZATION OF OLEFINS, AND METHOD FOR OLIGOMERIZATION OF OLEFINS USING THE CATALYST SYSTEM (AS AMENDED) | LG CHEM, LTD. (KR) | 2017-02-02 | — | — | US | claimed |
| EP-3101039-A1 | LIGAND COMPOUND, ORGANIC CHROME COMPOUND, CATALYST SYSTEM FOR OLEFIN OLIGOMERIZATION, AND METHOD FOR OLIGOMERIZING OLEFIN USING SAME | LG Chem, Ltd. (KR) | 2016-12-07 | — | — | EP | claimed |
| US-9421533-B2 | Catalyst or synthesizing 1-hexene from ethylene trimerization and application thereof | PETROCHINA COMPANY LIMITED (CN) | 2016-08-23 | — | — | US | claimed |
| CN-105085576-A | Pyridinamine-based chromium complex and preparation method and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2015-11-25 | — | — | CN | claimed |
| EP-2639213-A1 | METHOD FOR PREPARING 1-OCTENE BY OLIGOMERIZATION OF ETHYLENE | Petrochina Company Limited (CN) | 2013-09-18 | — | — | EP | claimed |
| US-20130090508-A1 | Method for Preparing 1-Octene by Oligomerization of Ethylene | PETROCHINA COMPANY LIMITED (CN) | 2013-04-11 | — | — | US | claimed |
| US-20120310025-A1 | Catalyst for Synthesizing 1-Hexene from Ethylene Trimerization and Application Thereof | PETROCHINA COMPANY LIMITED (CN) | 2012-12-06 | — | — | US | claimed |
| EP-2520366-A1 | CATALYST FOR SYNTHESIZING 1-HEXENE FROM ETHYLENE TRIMERIZATION AND APPLICATION THEREOF | Petrochina Company Limited (CN) | 2012-11-07 | — | — | EP | claimed |
| CN-1357556-A | Chromium diimine olefine polymerizing catalyst | CHANGCHUN APPLIED CHEMISTRY (CN) | 2002-07-10 | — | — | CN | claimed |