Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15821343 | 0.88 | ALDH1A1 (0.43) | MAPTSMN1; SMN2RAB9AKMT2ALMNA | |
| SCHEMBL8089868 | 0.86 | MAPT (0.44) | HSD17B1MAPTSMN1; SMN2HPGDRAB9A | |
| SCHEMBL15819249 | 0.84 | ALDH1A1 (0.44) | MAPTL3MBTL1XDH | |
| SCHEMBL15819518 | 0.84 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2HPGDRAB9AKMT2A | |
| SCHEMBL15826426 | 0.82 | HSD17B1 (0.32) | HSD17B1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL15819482 | 0.80 | MAPT (0.44) | HSD17B1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL6611172 | 0.78 | MAPT (0.57) | HSD17B1MAPTSMN1; SMN2HPGDRAB9A | |
| SCHEMBL4803948 | 0.74 | CES2 (0.47) | MAPTSMN1; SMN2KMT2AKIF11XDH | |
| SCHEMBL4064595 | 0.72 | CYP2A6 (0.42) | MAPTSMN1; SMN2HPGDRAB9AKMT2A | |
| SCHEMBL6152607 | 0.72 | MAPT (0.39) | MAPTSMN1; SMN2HPGDRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014100833-A1 | BENZAMIDE COMPOUNDS AND RELATED METHODS OF USE | NORTHWESTERN UNIVERSITY (US) | 2014-06-26 | — | — | WO | disclosed |
| US-8067611-B2 | Substituted 1-(thiazolyl)-and 1-(isothiazolyl)pyrazol-4-ylacetic acids, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20100197501-A1 | SUBSTITUTED 1-(THIAZOLYL)-AND 1-(ISOTHIAZOLYL)PYRAZOL-4-YLACETIC ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197501-A1 | SUBSTITUTED 1-(THIAZOLYL)-AND 1-(ISOTHIAZOLYL)PYRAZOL-4-YLACETIC ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | THRA, TSHR, DDT | HSD17B1 1810/4885MAPT 4674/4885SMN1; SMN2 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.