Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 7/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | TTR | P02766 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.49 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.49 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333015 | 1.00 | CXCL8 (0.49) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL2558800 | 0.85 | MEN1 (0.46) | CXCL8PTGS2PTGS1CYP2C9BLM | |
| SCHEMBL8349866 | 0.80 | PTGS2 (0.59) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL4333864 | 0.80 | LMNA (0.60) | CYP2C9BLMGAATSHRKMT2A | |
| SCHEMBL11218459 | 0.79 | CXCL8 (0.46) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL7760481 | 0.78 | ALDH1A1 (0.55) | CXCL8PTGS2CYP2C9BLMGAA | |
| SCHEMBL7351378 | 0.77 | CXCL8 (0.47) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL7351383 | 0.77 | CXCL8 (0.47) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL10439671 | 0.77 | CXCL8 (0.52) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL11403806 | 0.75 | CXCL8 (0.44) | CXCL8PTGS2TTRPTGS1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041576-A1 | 1-(2,6-DICHLOROPHENYL)-2-QUINOLINONEIMINE-3-CARBOXYLIC ACID, PRODUCTION PROCESS THEREFOR AND ANTI-INFLAMMATORY AND ANALGESIC COMPOSITION CONTAINING THE COMPOUND | DAITO KOEKI KABUSHIKI KAISHA (JP) | 1981-12-16 | — | — | EP | claimed |
| US-4188343-A | Process for preparing anthranylaldehyde derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1980-02-12 | — | — | US | claimed |
| JP-57064647-A | — | — | None | — | — | JP | disclosed |
| JP-54160340-A | — | — | None | — | — | JP | disclosed |
| JP-59084823-A | — | — | None | — | — | JP | disclosed |
| JP-56055373-A | — | — | None | — | — | JP | disclosed |
| JP-55022629-A | — | — | None | — | — | JP | disclosed |
| JP-55022628-A | — | — | None | — | — | JP | disclosed |
| JP-56115772-A | — | — | None | — | — | JP | disclosed |
| CN-119688876-A | Method for measuring related substances in diclofenac sodium gel | 药大制药有限公司 | 2025-03-25 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| JP-S56115772-A | NOVEL PREPARATION OF SUBSTITUTED INDOLINONE | ZENYAKU KOGYO KK | 1981-09-11 | — | — | JP | disclosed |
| JP-S5655373-A | QUINOLINONEIMINECARBOXYLIC ACID, ITS PREPARATION, AND ANTIPHLOGISTIC AND ANALGESIC COMPOSITION CONTAINING SAID COMPOUND | DAITO KOEKI KK | 1981-05-15 | — | — | JP | disclosed |
| US-4242522-A | O-(N-Allyl-2,6-dichloroanilino)phenylacetic acid derivative and a process for preparing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1980-12-30 | — | — | US | disclosed |
| US-4189595-A | [N-benzyl-o-(2,6-dichloroanilino)phenyl]acetic acid derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1980-02-19 | — | — | US | disclosed |
| JP-S5522628-A | GLYCIDATE AND ITS PREPARATION | DAITO KOEKI KK | 1980-02-18 | — | — | JP | disclosed |
| JP-S5522629-A | PREPARATION OF 2(2,6-DICHLOROANILINO)PHENYL ACETIC ACID | DAITO KOEKI KK | 1980-02-18 | — | — | JP | disclosed |
| US-4188343-A | Process for preparing anthranylaldehyde derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1980-02-12 | — | — | US | disclosed |
| US-4188343-A | Process for preparing anthranylaldehyde derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1980-02-12 | — | — | US | disclosed |
| JP-S54160340-A | PREPARATION OF 1-ALKYLSULFINYL-1-ALKYLTHIO-2-N-BENZYL-O- (2,6-DICHLOROANILINO)PHENYL-ETHYLENE | NISSAN CHEM IND LTD | 1979-12-19 | — | — | JP | disclosed |