Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TOP2A | P11388 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208445 | 0.83 | CYP4F2 (0.60) | KMT2AMAPTTOP2AKDM4EPOLB | |
| Quinoline SCHEMBL28119523 | 0.81 | TOP2A (0.52) | KMT2AMAPTTOP2AKDM4EPOLB | |
| Ether SCHEMBL2007543 | 0.80 | LOXL2 (0.46) | MAPTKDM4ERAB9AALDH1A1SMN1; SMN2 | |
| Alcohol SCHEMBL28501888 | 0.80 | LOXL2 (0.48) | MAPTKDM4ERAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5717650 | 0.80 | CYP4F2 (0.63) | KMT2AMAPTTOP2AKDM4EPOLB | |
| SCHEMBL6174947 | 0.79 | PKM (0.54) | KMT2AMAPTTOP2AKDM4EPOLB | |
| O-Xylene SCHEMBL30462319 | 0.78 | CYP4F2 (0.54) | KMT2AMAPTTOP2AKDM4ECYP4F2 | |
| SCHEMBL29578471 | 0.78 | NCF1 (0.56) | MAPTKDM4ERAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL19745058 | 0.78 | NCF1 (0.56) | MAPTKDM4ERAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9815408 | 0.78 | NCF1 (0.56) | MAPTKDM4ERAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067602-B2 | Asymmetric cyanine fluorescent dyes, compositions and their use in staining biological samples | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2011-11-29 | — | — | US | disclosed |
| US-20090176270-A1 | ASYMMETRIC CYANINE FLUORESCENT DYES, COMPOSITIONS AND THEIR USE IN STAINING BIOLOGICAL SAMPLES | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176270-A1 | ASYMMETRIC CYANINE FLUORESCENT DYES, COMPOSITIONS AND THEIR USE IN STAINING BIOLOGICAL SAMPLES | IK, CRY1, CRY2 | KMT2A 1735/4885MAPT 2490/4885TOP2A 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.