Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4139997 | 0.83 | L3MBTL1 (0.41) | RAPGEF4GAATRPA1ALOX5PTGS1 | |
| SCHEMBL19361218 | 0.81 | ALDH1A1 (0.41) | RAPGEF4GAAMAPTNPSR1L3MBTL1 | |
| SCHEMBL1607447 | 0.76 | ESR2 (0.41) | RAPGEF4TRPA1ALOX5PTGS1PTGS2 | |
| SCHEMBL17922517 | 0.74 | L3MBTL1 (0.55) | RAPGEF4TRPA1ALOX5PTGS1PTGS2 | |
| SCHEMBL16587989 | 0.74 | ALDH1A1 (0.46) | GAAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL9297946 | 0.73 | RAPGEF4 (0.55) | RAPGEF4GAACYTH2MEN1KMT2A | |
| SCHEMBL22015596 | 0.73 | PDIA6 (0.53) | TRPA1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7875384 | 0.72 | GAA (0.49) | RAPGEF4GAAPTGS1CYTH2L3MBTL1 | |
| SCHEMBL21276078 | 0.70 | L3MBTL1 (0.41) | RAPGEF4TRPA1ALOX5PTGS1PTGS2 | |
| SCHEMBL13044489 | 0.69 | RAPGEF4 (0.53) | RAPGEF4GAANR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155502-A1 | FUNCTIONALIZED MAIN CHAIN POLYMERS | Häring, Thomas (DE) | 2014-06-05 | — | — | US | disclosed |
| US-7615599-B2 | Noncrosslinked, covalently crosslinked and/or ionically crosslinked polymer which can be used in direct methanol fuel cells; sulfonated polyetherketones and sulfonated polysulfones; acid doped polymer has high mechanical stability and a low permeability for hydrogen, oxygen and methanol | HAERING THOMAS | 2009-11-10 | — | — | US | disclosed |
| US-20070208153-A1 | Functionalized Main Chain Polymers | HARING THOMAS | 2007-09-06 | — | — | US | disclosed |
| US-7196151-B2 | Functionalized main chain polymers | HAERING THOMAS | 2007-03-27 | — | — | US | disclosed |