Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.94 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.94 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.94 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.94 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.94 |
| ▸ | NPC1 | O15118 | 1/20 | 0.94 |
| ▸ | MLNR | O43193 | 1/20 | 0.94 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.94 |
| ▸ | EGFR | P00533 | 1/20 | 0.94 |
| ▸ | LMNA | P02545 | 1/20 | 0.94 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.94 |
| ▸ | FYN | P06241 | 1/20 | 0.94 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.94 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.94 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.94 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.94 |
| ▸ | HTR1A | P08908 | 1/20 | 0.94 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.94 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.94 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ebastine SCHEMBL18467 | 0.97 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BSLC6A4SLC6A3 | |
| Ebastine SCHEMBL25205252 | 0.96 | ADRA1D (0.98) | ADRA1DADRA1AADRA1BSLC6A4SLC6A3 | |
| Ebastine SCHEMBL2546560 | 0.95 | ADRA1D (0.96) | ADRA1DADRA1AADRA1BSLC6A4SLC6A3 | |
| SCHEMBL12197484 | 0.94 | CHRM2 (0.94) | ADRA1DADRA1AADRA1BSLC6A4SLC6A3 | |
| Ebastine SCHEMBL2471948 | 0.93 | ADRA1D (0.93) | ADRA1DADRA1AADRA1BSLC6A4SLC6A3 | |
| Ebastine SCHEMBL25228349 | 0.93 | DRD2 (0.93) | ADRA1DADRA1AADRA1BSLC6A4SLC6A3 | |
| Ebastine SCHEMBL25207151 | 0.92 | ADRA1D (0.91) | ADRA1DADRA1AADRA1BSLC6A4SLC6A3 | |
| Ebastine SCHEMBL2475732 | 0.92 | ADRA1D (0.91) | ADRA1DADRA1AADRA1BSLC6A4SLC6A3 | |
| Ebastine SCHEMBL25199696 | 0.92 | ADRA1D (0.91) | ADRA1DADRA1AADRA1BSLC6A4SLC6A3 | |
| Ebastine SCHEMBL28531760 | 0.92 | ADRA1D (0.91) | ADRA1DADRA1AADRA1BSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067604-B2 | Process for production of carebastine | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20110065923-A1 | PROCESS FOR PRODUCTION OF CAREBASTINE | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-03-17 | — | — | US | disclosed |
| US-7858798-B2 | metabolite of ebastine | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-20090137813-A1 | PROCESS FOR PRODUCTION OF CAREBASTINE | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-05-28 | — | — | US | disclosed |
| US-7498443-B2 | Process for production of carebastine | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-03-03 | — | — | US | disclosed |
| WO-2006034091-A2 | PROCESS FOR PRODUCTION OF CAREBASTINE | AMR TECHNOLOGY, INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| US-20060063933-A1 | Process for production of carebastine | AMR TECHNOLOGY, INC. (US) | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137813-A1 | PROCESS FOR PRODUCTION OF CAREBASTINE | GABRE, GABRB3, GABRB2 | ADRA1D 1305/4885ADRA1A 1947/4885ADRA1B 561/4885 |
| US-20060063933-A1 | Process for production of carebastine | GABRE, GABRB3, GABRB2 | ADRA1D 1305/4885ADRA1A 1947/4885ADRA1B 561/4885 |
| US-20110065923-A1 | PROCESS FOR PRODUCTION OF CAREBASTINE | GABRE, GABRB3, GABRB2 | ADRA1D 1305/4885ADRA1A 1947/4885ADRA1B 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.