Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25425656 | 0.87 | LIPG (0.40) | LIPGLPLALDH1A1MEN1KMT2A | |
| SCHEMBL3399375 | 0.85 | LIPG (0.42) | LIPGLPLMEN1KMT2AOPRM1 | |
| SCHEMBL3399142 | 0.85 | LIPG (0.42) | LIPGLPLMEN1KMT2AOPRM1 | |
| SCHEMBL1363047 | 0.79 | USP30 (0.40) | LIPGLPL | |
| SCHEMBL8020161 | 0.79 | USP30 (0.40) | LIPGLPL | |
| SCHEMBL3045151 | 0.78 | LIPG (0.47) | LIPGLPLALDH1A1MEN1KMT2A | |
| SCHEMBL1363051 | 0.76 | LIPG (0.41) | LIPGLPLALDH1A1MEN1KMT2A | |
| SCHEMBL4281413 | 0.75 | DPP4 (0.45) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL12062822 | 0.74 | LIPG (0.38) | LIPGLPLOPRM1OPRK1 | |
| SCHEMBL3041956 | 0.73 | GLS (0.47) | LIPGLPLALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067408-B2 | Dual pharmacophores—PDE4-muscarinic antagonistics | GLAXO GROUP LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |