Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 7/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399142 | 1.00 | LIPG (0.42) | LIPGLPLMGLLPTGDR2OPRM1 | |
| SCHEMBL25425656 | 0.87 | LIPG (0.40) | LIPGLPLOPRM1OPRK1MEN1 | |
| SCHEMBL1363047 | 0.86 | USP30 (0.40) | LIPGLPLMGLLPTGDR2CCR1 | |
| SCHEMBL8020161 | 0.86 | USP30 (0.40) | LIPGLPLMGLLPTGDR2CCR1 | |
| SCHEMBL12062822 | 0.86 | LIPG (0.38) | LIPGLPLMGLLPTGDR2OPRM1 | |
| SCHEMBL1363050 | 0.85 | LIPG (0.39) | LIPGLPLOPRM1OPRK1MEN1 | |
| SCHEMBL3045151 | 0.82 | LIPG (0.47) | LIPGLPLMEN1KMT2A | |
| SCHEMBL4055766 | 0.80 | KDM4E (0.52) | MGLLMEN1KMT2A | |
| SCHEMBL14645770 | 0.78 | MGLL (0.56) | MGLLPTGDR2CCR1CHRM4 | |
| SCHEMBL722120 | 0.76 | LPL (0.52) | LIPGLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2249647-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | Glaxo Group Limited (GB) | 2010-11-17 | — | — | EP | disclosed |
| EP-2249646-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | Glaxo Group Limited (GB) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009100169-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009100168-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |