Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.33 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.33 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11893154 | 0.93 | DHODH (0.41) | EGLN1DHODHPKMCTSBCAPN1 | |
| SCHEMBL13630650 | 0.91 | PKM (0.41) | EGLN1PKMCTSBCAPN1SLC2A1 | |
| SCHEMBL10140229 | 0.91 | DHODH (0.37) | EGLN1DHODHPKMSLC2A1SLC2A2 | |
| SCHEMBL16606345 | 0.90 | SORT1 (0.40) | DHODHPKMSLC2A1SLC2A2SLC2A3 | |
| SCHEMBL13442912 | 0.89 | DHODH (0.37) | DHODHPKMSLC2A1SLC2A2SLC2A3 | |
| SCHEMBL10140235 | 0.88 | PDE4A (0.36) | EGLN1DHODHPKMCAPN1TNF | |
| SCHEMBL13592401 | 0.87 | EGLN1 (0.38) | EGLN1KMT2AMAPK14 | |
| SCHEMBL14524810 | 0.87 | DHODH (0.41) | EGLN1DHODHPKMSLC2A1SLC2A2 | |
| SCHEMBL28425563 | 0.86 | DHODH (0.41) | EGLN1DHODHCTSBCAPN1NTRK1 | |
| SCHEMBL11893155 | 0.85 | EGLN1 (0.37) | EGLN1DHODHPKMCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275471-A1 | ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275471-A1 | ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL PROPERTIES | AADAC, ACHE, NAAA | EGLN1 203/4885DHODH 1041/4885PKM 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.