Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563173 | 0.93 | DHODH (0.41) | PDE4AEGLN1DHODHPKMKCNH2 | |
| SCHEMBL30078383 | 0.93 | DHODH (0.41) | PDE4AEGLN1DHODHPKMKCNH2 | |
| SCHEMBL14227757 | 0.93 | DHODH (0.39) | PDE4AEGLN1DHODHPKMKCNH2 | |
| SCHEMBL11893257 | 0.93 | PDE4A (0.36) | PDE4AEGLN1DHODHPKMKCNH2 | |
| SCHEMBL10140229 | 0.91 | DHODH (0.37) | EGLN1DHODHPKMKCNH2SORT1 | |
| SCHEMBL10140240 | 0.90 | KMT2A (0.35) | PDE4AEGLN1PKMKCNH2PDE4B | |
| SCHEMBL16606345 | 0.90 | SORT1 (0.40) | DHODHPKMSORT1JAK2JAK1 | |
| SCHEMBL13442912 | 0.89 | DHODH (0.37) | PDE4ADHODHPKMPDE4BPDE4C | |
| SCHEMBL10140140 | 0.89 | SORT1 (0.39) | PDE4ADHODHPKMKCNH2CAPN1 | |
| SCHEMBL13630504 | 0.88 | EGLN1 (0.37) | EGLN1DHODHPKMCAPN1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949482-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-03-16 | — | — | US | disclosed |
| US-20160302414-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2016-10-20 | — | — | US | disclosed |
| US-9282743-B2 | Chemical compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-15 | — | — | US | disclosed |
| US-9096525-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140148339-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-29 | — | — | US | disclosed |
| US-8536089-B2 | For controlling phytopathogenic diseases; synergistic | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-17 | — | — | US | disclosed |
| US-20130210625-A1 | SPIROHETEROCYCLIC PYRROLIDINE DERIVATIVES BASED PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-15 | — | — | US | disclosed |
| US-8124567-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124566-B2 | Synergistic fungicidal compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20080076664-A1 | Fungicidal Compositions | SYNGENTA CROP PROTECTION, INC. | 2008-03-27 | — | — | US | disclosed |
| US-20080070785-A1 | For controlling phytopathogenic diseases; synergistic | SYNGENTA CROP PROTECTION, INC. (US) | 2008-03-20 | — | — | US | disclosed |
| US-20070265267-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070244121-A1 | Synergistic Fungicidal Compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130210625-A1 | SPIROHETEROCYCLIC PYRROLIDINE DERIVATIVES BASED PESTICIDES | DDT, PYCR1, PKD2 | PDE4A 814/4885EGLN1 1982/4885DHODH 248/4885 |
| US-20160302414-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, CASP3 | PDE4A 937/4885EGLN1 869/4885DHODH 1693/4885 |
| US-20070265267-A1 | FUNGICIDAL COMPOSITIONS | CRY1, ERG28, DDT | PDE4A 3336/4885EGLN1 1174/4885DHODH 2433/4885 |
| US-20070244121-A1 | Synergistic Fungicidal Compositions | DDT, CRY1, HCN1 | PDE4A 3034/4885EGLN1 2039/4885DHODH 1980/4885 |
| US-20080070785-A1 | For controlling phytopathogenic diseases; synergistic | BROX, EPM2A, MANBA | PDE4A 1356/4885EGLN1 1009/4885DHODH 2383/4885 |
| US-20140148339-A1 | CHEMICAL COMPOUNDS | DDT, CYP1B1, CYP1A1 | PDE4A 1985/4885EGLN1 258/4885DHODH 132/4885 |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | PIK3C3, CYP51A1, CYP1B1 | PDE4A 504/4885EGLN1 457/4885DHODH 874/4885 |
| US-20080076664-A1 | Fungicidal Compositions | AKR7A2, CYP51A1, TUBA3C | PDE4A 3169/4885EGLN1 1680/4885DHODH 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.