Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.35 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.35 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630504 | 0.91 | EGLN1 (0.37) | PKMEGLN1JAK2JAK1TYK2 | |
| SCHEMBL11893155 | 0.86 | EGLN1 (0.37) | PKMEGLN1KMT2ACTSBCAPN1 | |
| SCHEMBL11893224 | 0.86 | PKM (0.40) | PKMEGLN1JAK2JAK1TYK2 | |
| SCHEMBL11893154 | 0.85 | DHODH (0.41) | PKMEGLN1KMT2ACTSBCAPN1 | |
| SCHEMBL12522596 | 0.85 | EGLN1 (0.36) | PKMEGLN1KMT2ACTSBCAPN1 | |
| SCHEMBL12956899 | 0.83 | PKM (0.42) | PKMJAK2JAK1TYK2JAK3 | |
| SCHEMBL13913221 | 0.81 | PKM (0.36) | PKMEGLN1JAK2JAK1TYK2 | |
| SCHEMBL10140237 | 0.81 | KMT2A (0.36) | PKMEGLN1JAK2JAK1TYK2 | |
| SCHEMBL10140229 | 0.81 | DHODH (0.37) | PKMEGLN1JAK2JAK1TYK2 | |
| SCHEMBL16606345 | 0.80 | SORT1 (0.40) | PKMJAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275471-A1 | ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275471-A1 | ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL PROPERTIES | AADAC, ACHE, NAAA | PKM 3496/4885EGLN1 203/4885JAK2 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.