Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634211 | 0.85 | HRH4 (0.39) | HRH4HRH3LRRK2 | |
| SCHEMBL13634313 | 0.83 | CNR2 (0.37) | HRH4HRH3 | |
| SCHEMBL13634304 | 0.82 | HRH4 (0.38) | HRH4HRH3 | |
| SCHEMBL13634305 | 0.80 | GPR119 (0.43) | HRH4EGFRHRH3 | |
| SCHEMBL13634333 | 0.77 | HRH4 (0.31) | HRH4 | |
| SCHEMBL13634210 | 0.77 | HRH3 (0.33) | HRH4HRH3 | |
| SCHEMBL13162584 | 0.76 | IRAK4 (0.36) | EGFRGRIA1 | |
| SCHEMBL13162786 | 0.76 | EGFR (0.31) | EGFR | |
| SCHEMBL13634239 | 0.76 | AOC3 (0.35) | HRH4HRH3 | |
| SCHEMBL13634240 | 0.75 | HRH4 (0.33) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |