Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634313 | 0.88 | CNR2 (0.37) | HRH3HRH4 | |
| SCHEMBL13634305 | 0.84 | GPR119 (0.43) | HRH3CDK1CDK2HRH4 | |
| SCHEMBL13634321 | 0.81 | CHRM3 (0.31) | HRH3 | |
| SCHEMBL13270551 | 0.77 | CHRM3 (0.33) | — | |
| SCHEMBL13634262 | 0.77 | HRH4 (0.35) | HRH3HRH4 | |
| SCHEMBL13634211 | 0.76 | HRH4 (0.39) | HRH3HRH4 | |
| SCHEMBL13634304 | 0.75 | HRH4 (0.38) | HRH3HRH4 | |
| SCHEMBL13612636 | 0.75 | HTR6 (0.44) | HRH4 | |
| SCHEMBL13634366 | 0.74 | PDE9A (0.30) | — | |
| SCHEMBL13634239 | 0.73 | AOC3 (0.35) | HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |